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(-)-Epicatechin gallate

(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) 抑制环加氧酶-1 的IC50值为 7.5 μM。

CAS号

1257-08-5

分子式

C22H18O10

主要靶点

Autophagy|COX|Virus Protease

仅限科研使用

Cat No : CM00409

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Synonyms

Epicatechin gallate|Epicatechin 3-gallate|Epicatechin 3-O-gallate|inhibit|Inhibitor|ECG|Cyclooxygenase|COX|(−)-Epicatechin 3-gallate|( ) Epicatechin gallate|(-)-Epicatechin 3-gallate|(-)-Epicatechin 3-O-gallate|()Epicatechin gallate|Autophagy|表儿茶素没食子酸酯|Virus Protease|VirusProtease

验证数据展示

  • CAS No.: 1257-08-5

    (-)-Epicatechin gallate
    CAS#: 1257-08-5

产品信息

(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions.

CAS号 1257-08-5
分子式 C22H18O10
主要靶点 Autophagy|COX|Virus Protease
主要通路 神经科学|免疫与炎症|微生物学|自噬
分子量 442.37
纯度 99.50%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
别名 Epicatechin gallate|Epicatechin 3-gallate|Epicatechin 3-O-gallate|inhibit|Inhibitor|ECG|Cyclooxygenase|COX|(−)-Epicatechin 3-gallate|( ) Epicatechin gallate|(-)-Epicatechin 3-gallate|(-)-Epicatechin 3-O-gallate|()Epicatechin gallate|Autophagy|表儿茶素没食子酸酯|Virus Protease|VirusProtease

靶点活性

COX-1:7.5 μM.

溶解度

H2O:2.5 mg/mL (5.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.04 mM);DMSO:131 mg/mL (296.13 mM)

参考文献

1.Rosado H, et al. Int J Mol Sci. 2015 Jul 23;16(8):16710-27.
2.Hwang Y H, Jang S A, Kim T, et al. Anti-osteoporotic and Anti-adipogenic Effects of Rhus chinensis Nutgalls in Ovariectomized Mice Fed with a High-fat Diet[J]. Planta medica. 2019.

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