Recombinant Human RRAS protein (rFc Tag)
种属
Human
纯度
>85 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >85 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human RRAS protein Asp23-Ser201 (Accession# P10301) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 6237 |
| 蛋白编号 | P10301 |
| 预测分子量 | 45.5 kDa |
| SDS-PAGE | 44-53 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Ras-related protein R-Ras2 (RRAS2) is also named TC21 and Teratocarcinoma oncogene. The RRAS2 member of the RAS-related subfamily, also known as TC21, is a close relative of the classic RAS GTPases (PMID: 3898776). RRAS2, a member of the R-Ras subfamily of Ras-like low-molecular-weight GTPases, is located in the plasma membrane and functions as a signal transducer (PMID: 38601074). RRAS2 is GTP-binding protein with GTPase activity, involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes (PMID: 31130282).
参考文献:
1. Colicelli, John. Science's STKE 2004.250 (2004): re13-re13. 2. Pfeil, Alexander J., et al. Clinical Cancer Research (2026). 3. Xiao, Ruowen, et al. Translational Cancer Research 8.2 (2019): 664. 4. Flex, Elisabetta, et al. Human molecular genetics 23.16 (2014): 4315-4327. 5. Miller, John P., et al. PLoS genetics 8.11 (2012): e1003042.
