Recombinant Human CNTN2 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human CNTN2 protein Ser31-Asn1012 (Accession# Q02246) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 6900 |
| 蛋白编号 | Q02246 |
| 预测分子量 | 133.0 kDa |
| SDS-PAGE | 130-180 kDa , reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Contactin-2 (CNTN2), also known as CNTN2 or axonal glycoprotein TAG-1, is a cell adhesion molecule anchored within the cell membrane that is a member of the immunoglobulin family. It is reported to be transiently expressed in specific neurons during the fetal period. CNTN2 consists of six Ig domains followed by four fibronectin domains, and it is tethered to the cell surface by a glycosylphosphatidylinositol anchor. CNTN2 levels may reflect impairment of brain development and indirectly brain iron stores, which are likely deficient in infants of maternal IDA or chronic hypoxic states like IDMs.
参考文献:
1. Yan Y, Jiang Y. Int J Mol Med. 2016;37(1):251-257. 2. Lu Z, Reddy MV, Liu J, et al. J Biol Chem. 2016;291(46):24133-24147. 3. Gurung S, Asante E, Hummel D, et al. Mech Dev. 2018;152:1-12.
