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Recombinant Mouse Surfactant protein D protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2924

Print datasheet

Synonyms

Lung surfactant protein D, PSP-D, Pulmonary surfactant-associated protein D, Sftp4, Sftpd

验证数据展示

  • Purity of Recombinant Mouse Surfactant protein D was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse Surfactant protein D was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse Surfactant protein D protein Ala20-Phe374 (Accession# P50404) with a rabbit IgG Fc tag at the C-terminus.
基因ID 20390
蛋白编号 P50404
预测分子量 61.7 kDa
SDS-PAGE 67-75 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Surfactant Protein D (SP‐D) is a pattern recognition molecule that belongs to the collectin family expressed in multiple human organ systems, including alveolar type II cells and Clara cells. The surfactant protein D‐encoding gene (SFTPD) is located at the genomic position 10q22.2‐23.1. SP‐D plays an important role in the innate immune system by binding bacteria, viruses, fungi, and parasites for clearance via opsonization in phagocytes, as well as aiding in the removal of allergens.

参考文献:

1. Sorensen GL. (2018) Front Med. 5:18. 
2. Sorensen GL, et al. (2014) J Pediatr. 165(4):683‐689.
3. Wright JR. (2005) Nat Rev Immunol. 5(1):58‐68.
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