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Recombinant Human Lactoferrin/LTF protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0888

Print datasheet

Synonyms

Lactoferrin, LTF, EC:3.4.21.-, GIG 12, GIG12

验证数据展示

  • Purity of Recombinant Human Lactoferrin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Lactoferrin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human Lactoferrin protein Gly20-Lys710 (Accession# P02788-1) with a His tag at the C-terminus.
基因ID 4057
蛋白编号 P02788-1
预测分子量 77 kDa
SDS-PAGE 70-90 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Lactoferrin (LTF), known as an iron-binding glycoprotein, is the most abundant element in milk. Prior research has illustrated that LTFbears multi-pharmacological properties, including protection against infection, regulation inflammatory response, antioxidant and antifibrotic process. Moreover, clinical trials have identified the safety of oral administration of bovine LTF and demonstrated the efficacy of LTF on anti-infection, treatment of inflammation, cancer, metabolic disorders.

参考文献:

1. Mayeur S. et al. (2016)  Antioxid Redox Signal. 24:813–36.
2. Ono T. et al. (2015) Br J Nutr. 114:159.
3. Yan D. et al. (2013) J Biol Chem. 288:31655–69.
4. Ochoa TJ. et al. (2012) Biochem Cell Biol. 90:457–67.
5. Ye T. et al. (2023) Theranostics. 13(10):3419-3433.