• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 60174-1-Ig (same clone as 60174-1-PBS)

    WB analysis using 60174-1-Ig (same clone as 60174-1-PBS)

    Untreated and PNGase F-treated lysates of NK-92 cells were subjected to SDS PAGE followed by western blot with 60174-1-Ig (CD122/IL2RB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60174-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50451-1

    Cytometric bead array standard curve of MP50451-1

    Cytometric bead array standard curve of MP50451-1, CD122/IL2RB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60174-3-PBS. Detection antibody: 60174-1-PBS. Standard:Ag3929. Range: 0.098-25 ng/mL.

  • Cytometric bead array standard curve of MP50451-2

    Cytometric bead array standard curve of MP50451-2

    Cytometric bead array standard curve of MP50451-2, CD122/IL2RB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60174-2-PBS. Detection antibody: 60174-1-PBS. Standard:Ag3929. Range: 0.098-50 ng/mL.

CD122/IL-2RB Monoclonal antibody, PBS Only (Detector)

CD122/IL-2RB Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 60174-1-PBS

产品说明书

CloneNo. 3A12C7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA

别名

IL2RB, IL 2RB, IL 2R subunit beta, IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

60174-1-PBS targets CD122/IL-2RB as part of a matched antibody pair:

MP50451-1: 60174-3-PBS capture and 60174-1-PBS detection (validated in Cytometric bead array)

MP50451-2: 60174-2-PBS capture and 60174-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD122/IL-2RB fusion protein Ag3929 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 2 receptor, beta
别名 IL2RB, IL 2RB, IL 2R subunit beta, IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta
计算分子量 551 aa, 61 kDa
观测分子量75 kDa, 61 kDa
GenBank蛋白编号BC025691
基因名称 IL2RB
Gene ID (NCBI) 3560
ENSEMBL Gene IDENSG00000100385
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP14784
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.