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验证数据展示

  • FC experiment of human PBMCs using 98488-3-RR (same clone as 98488-3-PBS)

    FC experiment of human PBMCs using 98488-3-RR (same clone as 98488-3-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human LILRB2/CD85d Rabbit RecAb (98488-3-RR, Clone:250299A6) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98488-3-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98488-3-RR (same clone as 98488-3-PBS)

    FC experiment of human PBMCs using 98488-3-RR (same clone as 98488-3-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human LILRB2/CD85d Rabbit RecAb (98488-3-RR, Clone: 250299A6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98488-3-PBS in a different storage buffer formulation.

Anti-Human LILRB2/CD85d Rabbit Recombinant Antibody, PBS Only

LILRB2/CD85d Uni-rAb® Recombinant Antibody for FC
Cat No. 98488-3-PBS

产品说明书

CloneNo. 250299A6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

LILRB2, CD85 antigen-like family member D, CD85d, ILT 4, ILT4

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98488-3-PBS targets LILRB2/CD85d in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg2839

Product name: Recombinant Human LILRB2/CD85d protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 22-458 aa of NM_005874.4

Sequence: QTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRH

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
别名 LILRB2, CD85 antigen-like family member D, CD85d, ILT 4, ILT4
计算分子量65 kDa
GenBank蛋白编号NM_005874.4
基因名称 LILRB2
Gene ID (NCBI) 10288
RRIDAB_3746118
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ8N423-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LILRB2 (Leukocyte immunoglobulin-like receptor subfamily B member 2), also known as ILT4, CD85d or MIR10, is a type I transmembrane glycoprotein that contains four extracellular immunoglobulin domains, a transmembrane domain, and three cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (PMID: 33928233). LILRB2 is mainly expressed in immunocytes including monocytes, macrophages, and dendritic cells, and transduces negative signals by its association with SHP-1 phosphatase via the ITIMs (PMID: 35717259). LILRB2 can interact with various ligands such as HLA-A, HLA-B, HLA-C, HLA-G, HLA-F, CD1c, CD1d, angiopoietin-like proteins (ANGPTLs), and SEMA4A.

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