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验证数据展示

  • FC experiment of human PBMCs using 98490-2-RR (same clone as 98490-2-PBS)

    FC experiment of human PBMCs using 98490-2-RR (same clone as 98490-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ENPP3/CD203c Rabbit RecAb (98490-2-RR, Clone: 242965D11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human IL3RA/CD123 Rabbit Recombinant Antibody (CL647-98107, Clone: 241268E3). Cells were not fixed. This data was developed using the same antibody clone with 98490-2-PBS in a different storage buffer formulation.

Anti-Human ENPP3/CD203c Rabbit Recombinant Antibody, PBS Only

ENPP3/CD203c Uni-rAb® Recombinant Antibody for FC
Cat No. 98490-2-PBS

产品说明书

CloneNo. 242965D11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

ENPP3, B10, CD203c, E NPP 3, PD IBETA

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98490-2-PBS targets ENPP3/CD203c in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg2369

Product name: recombinant human ENPP3 protein

Source: mammalian cells-derived, pHZ-KIsec-N-rFc

Tag: N-rFc

Domain: 48-875 aa of BC146579

Sequence: LEKQGSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 ectonucleotide pyrophosphatase/phosphodiesterase 3
别名 ENPP3, B10, CD203c, E NPP 3, PD IBETA
计算分子量 875 aa, 100 kDa
GenBank蛋白编号BC146579
基因名称 ENPP3
Gene ID (NCBI) 5169
RRIDAB_3746120
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO14638
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ENPP3, also known as CD203c, is part of ectonucleotide pyrophosphatases/phosphodiesterase (ENPP) family and plays a role in various physiological processes. Increased levels of ENPP3 have been observed in conditions, such as clear cell renal cell carcinoma, bile duct carcinoma, and colorectal cancer, positioning ENPP3 as a potential tumor marker (PMID: 38749434). Mice harboring a point mutant of ENPP3 that specifically abolishes its cGAMP hydrolase activity are more resistant to both primary tumor growth and metastasis in certain cancers (PMID: 38149831).

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