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验证数据展示

  • FC experiment of mouse bone marrow cells using 98272-1-RR (same clone as 98272-1-PBS)

    FC experiment of mouse bone marrow cells using 98272-1-RR (same clone as 98272-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD71 Rabbit Recombinant Antibody (98272-1-RR, Clone: 242122F6) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse TER-119. Cells were not fixed. This data was developed using the same antibody clone with 98272-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse bone marrow cells using 98272-1-RR (same clone as 98272-1-PBS)

    FC experiment of mouse bone marrow cells using 98272-1-RR (same clone as 98272-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD71 Rabbit Recombinant Antibody (98272-1-RR, Clone: 242122F6)(red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98272-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98272-1-RR

    Affinity and Kinetic Characterization of 98272-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98272-1-RR against Mouse CD71 were performed. The affinity constant is 0.88 nM.

Anti-Mouse CD71 Rabbit Recombinant Antibody, PBS Only

CD71 Uni-rAb® Recombinant Antibody for FC
Cat No. 98272-1-PBS

产品说明书

CloneNo. 242122F6

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

Tfrc, 242122F6, TFR, TFR1, TR

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98272-1-PBS targets CD71 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg1064

Product name: Recombinant Mouse Transferrin R protein (His Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: N-6*His

Domain: 89-763 aa of NM_011638.4

Sequence: CKRVEQKEECVKLAETEETDKSETMETEDVPTSSRLYWADLKTLLSEKLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFHEFKFSKVWRDEHYVKIQVKSSIGQNMVTIVQSNGNLDPVESPEGYVAFSKPTEVSGKLVHANFGTKKDFEELSYSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKNKFPVVEADLALFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFGKMEGSCPARWNIDSSCKLELSQNQNVKLIVKNVLKERRILNIFGVIKGYEEPDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDFGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPVDGKSLYRDSNWISKVEKLSFDNAAYPFLAYSGIPAVSFCFCEDADYPYLGTRLDTYEALTQKVPQLNQMVRTAAEVAGQLIIKLTHDVELNLDYEMYNSKLLSFMKDLNQFKTDIRDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLKLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transferrin receptor
别名 Tfrc, 242122F6, TFR, TFR1, TR
计算分子量86kDa
GenBank蛋白编号NM_011638.4
基因名称 CD71
Gene ID (NCBI) 22042
RRIDAB_3745938
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ62351
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.

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