×
Use Able AI chat for product recommendations

验证数据展示

  • FC experiment of BALB/c mouse splenocytes using 98409-2-RR (same clone as 98409-2-PBS)

    FC experiment of BALB/c mouse splenocytes using 98409-2-RR (same clone as 98409-2-PBS)

    1x10^6 Untreated or CD3/CD28 treated BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD134/OX40 Rabbit RecAb (98409-2-RR, Clone:242901A7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD4 (GK1.5) (APC-65104, Clone: GK1.5). Cells were not fixed. This data was developed using the same antibody clone with 98409-2-PBS in a different storage buffer formulation.

  • FC experiment of BALB/c mouse splenocytes using 98409-2-RR (same clone as 98409-2-PBS)

    FC experiment of BALB/c mouse splenocytes using 98409-2-RR (same clone as 98409-2-PBS)

    1x10^6 CD3/CD28 treated BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD134/OX40 Rabbit RecAb (98409-2-RR, Clone:242901A7) (red) and PE-Conjugated Goat Anti-Rabbit IgG(H+L), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). 1x10^6 untreated BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD134/OX40 Rabbit RecAb (98409-2-RR, Clone:242901A7) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98409-2-PBS in a different storage buffer formulation.

Anti-Mouse CD134/OX40 Rabbit Recombinant Antibody, PBS Only

CD134/OX40 Uni-rAb® Recombinant Antibody for FC
Cat No. 98409-2-PBS

产品说明书

CloneNo. 242901A7

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

CD134, Tnfrsf4, Ox40, OX40 antigen, OX40L receptor

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

98409-2-PBS targets CD134/OX40 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg2936

Product name: Recombinant Mouse CD134/OX40 protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 20-211 aa of NM_011659.2

Sequence: VTARRLNCVKHTYPSGHKCCRECQPGHGMVSRCDHTRDTLCHPCETGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTQDTVCRCRPGTQPRQDSGYKLGVDCVPCPPGHFSPGNNQACKPWTNCTLSGKQTRHPASDSLDAVCEDRSLLATLLWETQRPTFRPTTVQSTTVWPRTSELPSPPTLVTPEGP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 4
别名 CD134, Tnfrsf4, Ox40, OX40 antigen, OX40L receptor
计算分子量30 kDa
GenBank蛋白编号NM_011659.2
基因名称 CD134
Gene ID (NCBI) 22163
RRIDAB_3746050
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP47741
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).

||
New chat

Able™

正在加载，请稍候...