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SLC7A11/xCT Polyclonal antibody

SLC7A11/xCT Polyclonal Antibody for WB, IP, IHC, ELISA

Host / Isotype

Rabbit / IgG


human and More (2)


WB, IP, IHC, ELISA and More (3)



Cat No : 26864-1-AP

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Amino acid transport system xc, CCBR1, Cystine/glutamate transporter, SLC7A11, SLC7A11/xCT, xCT


Positive WB detected inA549 cells, U2OS cells, BxPC-3 cells, HepG2 cells
Positive IP detected inA549 cells, HepG2 cells
Positive IHC detected inhuman renal cell carcinoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.


26864-1-AP targets SLC7A11/xCT in WB, IHC, IP, CoIP, RIP, ELISA, IF applications and shows reactivity with human samples.

Tested Applications WB, IP, IHC, ELISA Application Description
Cited ApplicationsWB, IHC, IP, CoIP, RIP, IF
Tested Reactivity human
Cited Reactivityhuman, chicken, goat
Immunogen SLC7A11/xCT fusion protein Ag25431 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
Synonyms Amino acid transport system xc, CCBR1, Cystine/glutamate transporter, SLC7A11, SLC7A11/xCT, xCT
Calculated Molecular Weight 55 kDa
Observed Molecular Weight55 kDa, 35-40 kDa
GenBank Accession NumberBC012087
Gene Symbol SLC7A11
Gene ID (NCBI) 23657
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.


SLC7A11 (also known as xCT) is a membrane transporter involved in the uptake of cystine. It promotes glutathione synthesis through the uptake of cystine and the concomitant release of glutamate. This, in turn, protects cells from oxidative stress, maintains cellular redox balance, and prevents cell death induced by lipid peroxidation. SLC7A11 has been identified as a potential target for cancer therapeutics. It is overexpressed in multiple malignant tumors and is closely associated with the growth, prognosis, metastasis, and treatment response of various cancers including lung cancer. 26864-1-AP recognizes the 55 kDa and 35-40 kDa protein similar to the paper published (PMID: 32188872, 19156441).


Product Specific Protocols
WB protocol for SLC7A11/xCT antibody 26864-1-APDownload protocol
IHC protocol for SLC7A11/xCT antibody 26864-1-APDownload protocol
IP protocol for SLC7A11/xCT antibody 26864-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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  • KD Validated