Validation Data Gallery
Product Information
IL28-b is a recombinant mono-biotinylated anti IL28 Nanobody (VHH), suitable for ELISA, SPR, and BLI applications.
| Applications | BLI, SPR, ELISA |
| Reactivity | Human |
| Conjugate | Biotin |
| Type | Nanobody |
| Class | Recombinant |
| Host | Alpaca |
| Affinity | 9 nM |
| Molecular Weight | 15.0 kDa |
| Form | Liquid |
| RRID | AB_3665400 |
| Storage Buffer | 10 mM HEPES pH 7.0, 500 mM NaCl, 5 mM EDTA, 0.09% sodium azide |
| Storage Condition | Store at -20°C |
| Shipping | ambient |
| Background | IL28A, also named as IFNL2 and ZCYT020, is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. IL28A is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. It plays a significant role in the antiviral immune defense in the intestinal epithelium. |

