ZMAT3 Polyclonal antibody

ZMAT3 Polyclonal Antibody for IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IP, WB, ELISA and More (1)

Conjugate

Unconjugated

Cat No : 10504-1-AP

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Synonyms

p53 activated gene 608 protein, PAG608, WIG 1, WIG1, Zinc finger protein WIG 1, zinc finger, matrin type 3, ZMAT3



经过测试的应用

Positive WB detected inCOLO 320 cells, rat testis tissue, HEK-293 cells, HepG2 cells, mouse testis tissue
Positive IP detected inmouse testis tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:16000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10504-1-AP targets ZMAT3 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IP, WB, ELISA
Cited ApplicationsWB, IP, IF
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen ZMAT3 fusion protein Ag0780 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name zinc finger, matrin type 3
Synonyms p53 activated gene 608 protein, PAG608, WIG 1, WIG1, Zinc finger protein WIG 1, zinc finger, matrin type 3, ZMAT3
Calculated Molecular Weight 32 kDa
Observed Molecular Weight 32 kDa
GenBank Accession NumberBC002896
Gene Symbol ZMAT3
Gene ID (NCBI) 64393
RRIDAB_2217579
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9HA38
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ZMAT3 is a p53-induced zinc finger protein, and a role in the TP53-dependent growth regulatory pathway, contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. Acts as a bona fide target gene of p53/TP53.

实验方案

Product Specific Protocols
WB protocol for ZMAT3 antibody 10504-1-APDownload protocol
IP protocol for ZMAT3 antibody 10504-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouse

Mol Cell

Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.

Authors - Kathryn T Bieging-Rolett
humanWB

J Cell Mol Med

Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.

Authors - Jian Zhang
humanWB,IF,IP

FEBS Lett

The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA.

Authors - Prahl Magdalena M
ratWB

J Physiol Sci

Tolfenamic acid inhibits ROS-generating oxidase Nox1-regulated p53 activity in intrastriatal injection of malonic acid rats.

Authors - Xin Yang
humanWB

Cell Death Dis

MicroRNA-184 promotes apoptosis of trophoblast cells via targeting WIG1 and induces early spontaneous abortion.

Authors - Yuan Zhang