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验证数据展示

  • WB analysis of mouse lung using 20459-1-AP (same clone as 20459-1-PBS)

    WB analysis of mouse lung using 20459-1-AP (same clone as 20459-1-PBS)

    mouse lung tissue were subjected to SDS PAGE followed by western blot with 20459-1-AP (ZIP8 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20459-1-PBS in a different storage buffer formulation.

  • WB analysis using 20459-1-AP (same clone as 20459-1-PBS)

    WB analysis using 20459-1-AP (same clone as 20459-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20459-1-AP (ZIP8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20459-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 20459-1-AP (same clone as 20459-1-PBS)

    IHC staining of human kidney using 20459-1-AP (same clone as 20459-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20459-1-AP (ZIP8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20459-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse liver using 20459-1-AP (same clone as 20459-1-PBS)

    IP experiment of mouse liver using 20459-1-AP (same clone as 20459-1-PBS)

    IP result of anti-ZIP8 (IP:20459-1-AP, 4ug; Detection:20459-1-AP 1:500) with mouse liver tissue lysate 6000ug. This data was developed using the same antibody clone with 20459-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

ZIP8 Polyclonal antibody, PBS Only

ZIP8 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 20459-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, IP, Indirect ELISA

别名

BIGM103, SLC39A8, ZIP 8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

20459-1-PBS targets ZIP8 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag14292

Product name: Recombinant human SLC39A8 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 18-143 aa of BC012125

Sequence: LGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYGFLSVTIINLAS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 39 (zinc transporter), member 8
别名 BIGM103, SLC39A8, ZIP 8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6
计算分子量 460 aa, 50 kDa
观测分子量 42-46 kDa, 75-90 kDa,150 kDa
GenBank蛋白编号BC012125
基因名称 ZIP8
Gene ID (NCBI) 64116
RRIDAB_10697830
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9C0K1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC39A8, also known as ZIP8, belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that ZIP8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.

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