验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 25997-1-AP
产品信息
CL488-25997 targets XBP-1U specific in applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | XBP-1U specific fusion protein Ag21714 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | X-box binding protein 1 |
| 别名 | TREB5, X box binding protein 1, XBP 1, XBP1, XBP1s, XBP-1S, XBP1U, XBP-1U specific, XBP2 |
| 计算分子量 | 261 aa, 29 kDa |
| 观测分子量 | 32 kDa |
| GenBank蛋白编号 | BC000938 |
| 基因名称 | XBP1 |
| Gene ID (NCBI) | 7494 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P17861 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
X-box-binding protein 1 (XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa.