验证数据展示
产品信息
28156-1-PBS targets WNT3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | WNT3 fusion protein Ag27965 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | wingless-type MMTV integration site family, member 3 |
别名 | INT4, Proto oncogene Int 4 homolog, Proto oncogene Wnt 3, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3 |
计算分子量 | 355 aa, 40 kDa |
观测分子量 | 40-45 kDa |
GenBank蛋白编号 | BC114219 |
基因名称 | WNT3 |
Gene ID (NCBI) | 7473 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P56703 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
WNT3 is also named as INT4. WNT3 is required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis (PMID: 14872406). Wnt3 is up-regulated in cancer tissues, such as gastric cancer and lung cancer. Wnt3, as a member of Wnt family, has been proved to promote the stabilization of β-catenin to regulate the radiation sensitivity of cancer cells (PMID: 31851619).