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WDR77 Polyclonal antibody, PBS Only

WDR77 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 10115-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

WDR 77, WD45, WD repeat-containing protein 77, Nbla10071, Methylosome protein WDR77

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


产品信息

10115-1-PBS targets WDR77 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag0147

Product name: Recombinant human WDR77 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 92-342 aa of BC001679

Sequence: RGILVASDSGAVELWELDENETLIVSKFCKYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLVDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 WD repeat domain 77
别名 WDR 77, WD45, WD repeat-containing protein 77, Nbla10071, Methylosome protein WDR77
计算分子量 50 kDa
观测分子量40 kDa
GenBank蛋白编号BC001679
基因名称 WDR77
Gene ID (NCBI) 79084
RRIDAB_2215725
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BQA1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

WDR77, other named p44, MEP-50, is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. Normally, WDR77 locates in the nucleus, such as in prostate epithelial cells. However, it localized to the cytoplasm in prostatic intraepithelial neoplasia and prostate cancer cells. Nuclear WDR77 mediates the growth inhibition and differentiation. WDR may involve in the biogenesis of small nuclear ribonucleoprotein particles.

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