验证数据展示
经过测试的应用
| Positive WB detected in | fetal human brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
26817-1-AP targets WDR41 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human |
| 文献引用反应性 | human |
| 免疫原 | WDR41 fusion protein Ag25275 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | WD repeat domain 41 |
| 别名 | WD repeat-containing protein 41, WD repeat domain 41, MSTP048 |
| 计算分子量 | 459 aa, 52 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC040241 |
| 基因名称 | WDR41 |
| Gene ID (NCBI) | 55255 |
| RRID | AB_2880646 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9HAD4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
WDR41, or WD40 repeat-containing protein 41, is a protein that plays a role in regulating cellular processes, particularly in the context of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). It is part of a complex that includes C9ORF72 and SMCR8, which has been shown to regulate autophagy and function as a Rab GTPase-activating protein (GAP). The C9ORF72-SMCR8-WDR41 complex is believed to participate in the regulation of membrane trafficking and autophagy-lysosome pathway.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for WDR41 antibody 26817-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |