验证数据展示
产品信息
14766-1-AP targets WDR4 in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | WDR4 fusion protein Ag6531 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | WD repeat domain 4 |
| 别名 | TRM82, WD repeat containing protein 4, WD repeat domain 4, WDR4 |
| 计算分子量 | 30 kDa |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | BC001074 |
| 基因名称 | WDR4 |
| Gene ID (NCBI) | 10785 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P57081 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
A group of functionally diverse regulatory proteins in eukaryotes, defined by a conserved core of 4 or more modular repeat units, is known as the WD repeat family. Proteins belonging to the WD repeat family are involved in a number of cellular processes, including cell cycle progression, apoptosis, signal transduction, and gene regulation. WD repeat-containing protein 4 (WDR4) belongs to the WD repeat family, and is required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. It acts to stablize and induce conformation change of the catalytic subunit in the complex. There exists three isoforms, while isoform1, 2 are 45kDa band, and isoform 3 is 30 kDa band.