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VRK1 Polyclonal antibody

VRK1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human and More (2)

Applications

WB, ELISA and More (1)

Conjugate

Unconjugated

Cat No : 28018-1-AP

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Synonyms

vaccinia related kinase 1, VRK1



经过测试的应用

Positive WB detected inHeLa cells, Jurkat cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28018-1-AP targets VRK1 in WB, IHC, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA
Cited ApplicationsWB, IHC
Tested Reactivity Human
Cited Reactivityhuman, mouse
Immunogen VRK1 fusion protein Ag27754 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name vaccinia related kinase 1
Synonyms vaccinia related kinase 1, VRK1
Calculated Molecular Weight 396 aa, 45 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberBC103761
Gene Symbol VRK1
Gene ID (NCBI) 7443
RRIDAB_2918140
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ99986
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Vaccinia-related kinase 1 (VRK1) is a members of the vaccinia-related kinase (VRK) family of serine/threonine kinases and are principally localized in the nucleus. VRK1 was initially described as a kinase with homology to B1R, a vaccinia virus kinase required for viral DNA replication and the early phase of infection. It has been suggested that VRK1 was overexpressed in numerous human tumors, such as lung carcinomas, hepatocellular carcinoma, breast carcinomas, head and neck squamous cell carcinoma. (PMID: 28927264, PMID: 29103766)

实验方案

Product Specific Protocols
WB protocol for VRK1 antibody 28018-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
human,mouseWB,IHC

Can Respir J

Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage

Authors - Ning Du
  • KD Validated