验证数据展示
产品信息
85097-1-PBS targets VLDLR in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, FC (Intra), Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | very low density lipoprotein receptor |
| 别名 | Very low-density lipoprotein receptor, VLDL receptor, VLDL-R |
| 计算分子量 | 96 kDa |
| 观测分子量 | 120 kDa |
| GenBank蛋白编号 | NM_003383 |
| 基因名称 | VLDLR |
| Gene ID (NCBI) | 7436 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P98155 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The very low-density lipoprotein receptor (VLDLR) is a member of the LDL receptor family with a complex molecular weight profile due to post-translational modifications. The calculated molecular weight of the core protein is approximately 84-86 kDa, however, VLDLR undergoes extensive glycosylation during processing, resulting in higher apparent molecular weights observed in SDS-PAGE analyses. Multiple studies report that glycosylated VLDLR migrates as broad bands between 90-180 kDa under reducing conditions, with the most commonly observed forms at approximately 96 kDa (core glycosylated form), 115-135 kDa (mature fully glycosylated form), and 150-180 kDa (hyperglycosylated or dimeric forms).
