验证数据展示
产品信息
15950-1-PBS targets UTP23 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag8609 Product name: Recombinant human UTP23 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-249 aa of BC005955 Sequence: MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEEGNPHHYFVATQDQNLSVKVKKKPGVPLMFIIQNTMVLDKPSPKTIAFVKAVESGQLVSVHEKESIKHLKEEQGLVKNTEQSRRKKRKKISGPNPLSCLKKKKKAPDTQSSASEKRRKRKRIRNRSNPKVLSEKQNAEGE 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | UTP23, small subunit (SSU) processome component, homolog (yeast) |
| 别名 | rRNA-processing protein UTP23 homolog, C8orf53 |
| 计算分子量 | 249 aa, 28 kDa |
| 观测分子量 | 28 kDa, 17 kDa |
| GenBank蛋白编号 | BC005955 |
| 基因名称 | UTP23 |
| Gene ID (NCBI) | 84294 |
| RRID | AB_10644292 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BRU9 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
UTP23 is a component of ribosomal small-subunit processome, which is involved in ribosome synthesis and RNA maturation. UTP23 contains a long and likely unstructured tail at the C terminus of the PIN domain (PMID: 24152547). UTP23 is a target of genetic variation associated with colorectal cancer in chromosome 8q23.3, and it may coordinate with EIF3H in this region in the development of colorectal cancer. Low expression of UTP23 predicts poorer prognosis of ovarian cancer patients (PMID: 31540773, 37880005). It has 2 predicted molecular weight of 28 kDa and 17 kDa.
