验证数据展示
产品信息
20238-1-AP targets UNC5B-Specific in ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | unc-5 homolog B (C. elegans) |
| 别名 | Netrin receptor UNC5B, p53RDL1, Protein unc 5 homolog 2, Protein unc 5 homolog B, unc 5 homolog B (C. elegans), UNC5B, UNC5H2 |
| 计算分子量 | 104 kDa |
| GenBank蛋白编号 | NM_170744 |
| 基因名称 | UNC5B |
| Gene ID (NCBI) | 219699 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8IZJ1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
UNC5B, also named as P53RDL1 and UNC5H2, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. UNC5B mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. This antibody is specific to UNC5B.