验证数据展示
经过测试的应用
| Positive WB detected in | NCI-H1299 cells, mouse liver tissue, rat liver tissue, mouse kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
23765-1-AP targets UGT1A6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag20635 Product name: Recombinant human UGT1A6 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 176-488 aa of BC019861 Sequence: CSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMATADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | UDP glucuronosyltransferase 1 family, polypeptide A6 |
| 别名 | UDP-glucuronosyltransferase 1-6, Phenol-metabolizing UDP-glucuronosyltransferase, HLUGP1, HLUGP, GNT1 |
| 计算分子量 | 532 aa, 61 kDa |
| 观测分子量 | 70 kDa |
| GenBank蛋白编号 | BC019861 |
| 基因名称 | UGT1A6 |
| Gene ID (NCBI) | 54578 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P19224 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
UDP-glucuronosyltransferase 1-6 (UGT1A6, also known as GNT1 and UGT1) plays a crucial role in the glucuronidation of numerous drugs, toxins, and endogenous substrates. This process is essential for detoxifying and excreting lipophilic compounds, primarily in the liver (PMID: 15761114).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for UGT1A6 antibody 23765-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
