验证数据展示
产品信息
68565-1-PBS targets UBR2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | UBR2 fusion protein Ag13446 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | ubiquitin protein ligase E3 component n-recognin 2 |
别名 | KIAA0349, EC:2.3.2.27, E3 ubiquitin-protein ligase UBR2, C6orf133, bA49A4.1 |
计算分子量 | 439aa,50 kDa; 1755aa,201 kDa |
观测分子量 | 201 kDa |
GenBank蛋白编号 | BC064512 |
基因名称 | UBR2 |
Gene ID (NCBI) | 23304 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q8IWV8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
UBR2(Ubiquitin-protein ligase E3-alpha-2) is also named as C6orf133, KIAA0349 and N-recognin-2. It is a component of the N-end rule pathway and recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. It has four isoforms produced by alternative splicing.