Prealbumin/transthyretin Recombinant antibody, PBS Only (Detector)

Prealbumin/transthyretin Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA, Sample test
Cat No. 86273-1-PBS

产品说明书

CloneNo. 250820B6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA, Sample test

Prealbumin, transthyretin, TTR, ATTR, HsT2651

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


Planning an IHC experiment? We recommend our IHCeasy TTR Ready-To-Use IHC Kit. TTR primary antibody included.

产品信息

86273-1-PBS targets Prealbumin/transthyretin as part of a matched antibody pair:

MP02304-1: 86273-2-PBS capture and 86273-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA, Sample test Application Description
经测试反应性 human
免疫原 Prealbumin/transthyretin fusion protein Eg0931 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transthyretin
别名 Prealbumin, transthyretin, TTR, ATTR, HsT2651
计算分子量16 kDa
观测分子量 16 kDa
GenBank蛋白编号NM_000371.4
基因名称 TTR
Gene ID (NCBI) 7276
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP02766
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. However Western blot analysis using specific rabbit anti-mouse TTR reveals that TTR is absent from the cortex, hippocampus, and cerebellum and present in the choroid plexus. (PMID: 22103483, 16698124)

Loading...