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验证数据展示

  • FC experiment of Balb/c mouse peritoneal macrophages using 98018-1-RR (same clone as 98018-1-PBS)

    FC experiment of Balb/c mouse peritoneal macrophages using 98018-1-RR (same clone as 98018-1-PBS)

    1x10^6 Balb/c mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse TLR4/CD284 Rabbit Recombinant Antibody (98018-1-RR, Clone: 230463C7) or 0.25 ug Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD11b (M1/70) (APC-65055, Clone: M1/70). Cells were not fixed. This data was developed using the same antibody clone with 98018-1-PBS in a different storage buffer formulation.

  • FC experiment of Balb/c mouse peritoneal macrophages using 98018-1-RR (same clone as 98018-1-PBS)

    FC experiment of Balb/c mouse peritoneal macrophages using 98018-1-RR (same clone as 98018-1-PBS)

    1x10^6 Balb/c mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse TLR4/CD284 Rabbit Recombinant Antibody (98018-1-RR, Clone: 230463C7) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Isotype Control and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98018-1-PBS in a different storage buffer formulation.

Anti-Mouse TLR4/CD284 Rabbit Recombinant Antibody, PBS Only

TLR4/CD284 Uni-rAb® Recombinant Antibody for FC
Cat No. 98018-1-PBS

产品说明书

CloneNo. 230463C7

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

Tlr4, CD284, toll like receptor 4, 230463C7

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98018-1-PBS targets TLR4/CD284 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Ag32998

Product name: Recombinant mouse Tlr4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 198-395 aa of NM_021297

Sequence: RENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 toll-like receptor 4
别名 Tlr4, CD284, toll like receptor 4, 230463C7
计算分子量96 kDa
GenBank蛋白编号NM_021297
基因名称 Tlr4
Gene ID (NCBI) 21898
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ9QUK6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

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