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验证数据展示

  • WB analysis using 84929-6-RR (same clone as 84929-6-PBS)

    WB analysis using 84929-6-RR (same clone as 84929-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84929-6-RR (TYRO3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84929-6-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 84929-6-RR (same clone as 84929-6-PBS)

    IHC staining of mouse brain using 84929-6-RR (same clone as 84929-6-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84929-6-RR (TYRO3 antibody) at dilution of 1:250 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84929-6-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TYRO3 antibody included
  • IHC staining of mouse brain using 84929-6-RR (same clone as 84929-6-PBS)

    IHC staining of mouse brain using 84929-6-RR (same clone as 84929-6-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84929-6-RR (TYRO3 antibody) at dilution of 1:250 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84929-6-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TYRO3 antibody included
  • Affinity and Kinetic Characterization of 84929-6-RR

    Affinity and Kinetic Characterization of 84929-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84929-6-RR against Human TYRO3 were performed. The affinity constant is 0.133 nM.

TYRO3 Recombinant antibody, PBS Only

TYRO3 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84929-6-PBS

产品说明书

CloneNo. 242477G1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

RSE, EC:2.7.10.1, Dtk, BYK, Brt

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TYRO3 Ready-To-Use IHC Kit. TYRO3 primary antibody included.

产品信息

84929-6-PBS targets TYRO3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TYRO3 fusion protein Ag29527 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 TYRO3 protein tyrosine kinase
别名 RSE, EC:2.7.10.1, Dtk, BYK, Brt
计算分子量 97 kDa
观测分子量130 kDa
GenBank蛋白编号BC049368
基因名称 TYRO3
Gene ID (NCBI) 7301
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ06418
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TYRO3 has a structure includes a cytoplasmic domain and an extracellular ligand binding region. And ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. TYRO3 is associated with many physiological processes including cell survival, migration and differentiation. It has been reported that TYRO3 can be expressed in various regions of the mammalian central nervous system. The molecular mass of TYRO3 is 130 kDa, the apparent molecular mass is higher due to glycosylation.((PMID: 8873131, 23354874, 21539887)