验证数据展示
经过测试的应用
| Positive WB detected in | HeLa cells, U2OS cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
24707-1-AP targets TTYH3 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | TTYH3 fusion protein Ag18804 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tweety homolog 3 (Drosophila) |
| 别名 | hTTY3, KIAA1691, Protein tweety homolog 3, TTYH3, tweety homolog 3 (Drosophila) |
| 计算分子量 | 523 aa, 58 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC131824 |
| 基因名称 | TTYH3 |
| Gene ID (NCBI) | 80727 |
| RRID | AB_3085749 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9C0H2 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Tweety homologs (TTYHs) are conserved transmembrane proteins present in all eukaryotes including three members (TTYH1, TTYH2, and TTYH3) in humans. They are widely expressed in mammals including at high levels in the nervous system and have been implicated in cancers and other diseases including epilepsy, chronic pain, and viral infections. Physiologically, TTYH2 and TTYH3 are broadly expressed, while expression of TTYH1 is primarily limited to the nervous system, testes, and stem cells. TTYH3 is upregulated in gastric cancer with higher expression correlated with poor clinical outcomes. (PMID: 34824283)
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TTYH3 antibody 24707-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |