验证数据展示
产品信息
25713-1-PBS targets TTC7B in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag22388 Product name: Recombinant human TTC7B protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 96-318 aa of BC153122 Sequence: LQESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRVIAEAYATKGLCLEKLPISSSTSNLHVDREQDVITCYEKAGDIALLYLQEIERVILSNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPCQSPLDDPLRKGANTKTYTLTRRARVYSGENI 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tetratricopeptide repeat domain 7B |
| 别名 | c14_5685, Tetratricopeptide repeat protein 7-like-1, TPR repeat protein 7 like 1, TPR repeat protein 7B, TPR repeat protein 7-like-1 |
| 计算分子量 | 843 aa, 94 kDa |
| 观测分子量 | 50-53 kDa |
| GenBank蛋白编号 | BC153122 |
| 基因名称 | TTC7B |
| Gene ID (NCBI) | 145567 |
| RRID | AB_2880205 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q86TV6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TTC7B (Tetratricopeptide Repeat Domain 7B) is a protein-coding gene belonging to the tetratricopeptide repeat (TPR) family, which plays critical roles in cellular signaling, membrane dynamics, and disease pathogenesis. TTC7B is associated with focal adhesion (FA) disassembly and cell migration, promoting tumor invasion and metastasis. Its expression is tied to FA-related pathways like the PINCH-ILK-PARVIN complex (PMID: 37990988).


