×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of K-562 using 33274-1-AP (same clone as 33274-1-PBS)

    WB analysis of K-562 using 33274-1-AP (same clone as 33274-1-PBS)

    WB result of TSPYL6 antibody (33274-1-AP; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TSPYL6 transfected K-562 cells. This data was developed using the same antibody clone with 33274-1-PBS in a different storage buffer formulation.

  • WB analysis using 33274-1-AP (same clone as 33274-1-PBS)

    WB analysis using 33274-1-AP (same clone as 33274-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33274-1-AP (TSPYL6 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33274-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

TSPYL6 Polyclonal antibody, PBS Only

TSPYL6 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 33274-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

Testis-specific Y-encoded-like protein 6, TSPY Like 6, TSPY-like protein 6

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

33274-1-PBS targets TSPYL6 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag38157

Product name: Recombinant human TSPYL6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-410 aa of BC068576

Sequence: MSLPESPHSPATLDYALEDPHQGQRSREKSKATEVMADMFDGRLEPIVFPPPRLPEEGVAPQDPADGGHTFHILVDAGRSHGAIKAGQEVTPPPAEGLEAASASLTTDSSLKNGFPGEETHGLGGEKALETCGAGRSESEVIAEGKAEDVKPEECAMFSAPVDEKPGGEEMDVAEENRAIDEVNREAGPGPGPGPLNVGLHLNPLESIQLELDSVNAEADRALLQVERRFGQIHEYYLEQRNDIICNIPGFWVTAFRHHPQLSAMIRGQDAEMLSYLTNLEVKELRHPRTGCKFKFFFQRNPYFRNKLIVKVYEVRSFGQVVSFSTLIMWRRGHGPQSFIHRNRHVICSFFTWFSDHSLPESDRIAQIIKEDLWSNPLQYYLLGEDAHRARRRLVREPVEIPRPFGFQCG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TSPY-like 6
别名 Testis-specific Y-encoded-like protein 6, TSPY Like 6, TSPY-like protein 6
计算分子量 410 aa, 46 kDa
观测分子量60 kDa
GenBank蛋白编号BC068576
基因名称 TSPYL6
Gene ID (NCBI) 388951
RRIDAB_3742922
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ8N831
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TSPYL6 (TSPY-like 6) protein is a member of the TSPY-like nucleoprotein family, and its specific physiological function has not yet been fully elucidated. However, this protein has garnered significant attention in cancer research as "an important tumor biomarker". Studies have shown that TSPYL6 is frequently overexpressed in various malignant tumors, such as breast cancer, lung cancer, colorectal cancer, and hepatocellular carcinoma. Its overexpression promotes tumor cell proliferation, invasion, and metastasis, while inhibiting apoptosis, and is closely associated with poor patient prognosis. Mechanistically, TSPYL6 is believed to exert its cancer-promoting effects by influencing cell cycle progression (e.g., promoting the G1/S phase transition) and regulating key oncogenic signaling pathways such as Wnt/β-catenin. Therefore, TSPYL6 is not only a potential diagnostic and prognostic biomarker but also considered a potential therapeutic target for cancer.

||
New chat

Able™

正在加载，请稍候...