验证数据展示
产品信息
13036-1-PBS targets TSPAN3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag3689 Product name: Recombinant human TSPAN3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-253 aa of BC011206 Sequence: MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tetraspanin 3 |
| 别名 | Tspan-3, Transmembrane 4 superfamily member 8, TM4SF8, Tetraspanin-3, Tetraspanin TM4-A |
| 计算分子量 | 253 aa, 28 kDa |
| GenBank蛋白编号 | BC011206 |
| 基因名称 | TSPAN3 |
| Gene ID (NCBI) | 10099 |
| RRID | AB_3085406 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O60637 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Tetraspanin-3 (TSPAN3, also known as TM4SF8) is a member of the tetraspanin (TM4SF) family. Tetraspanins, so named because they contain four transmembrane domains, are frequently expressed at the cell surface in association with each other and with other molecules, and they function to regulate cell adhesion, migration, proliferation, and differentiation. TSPAN3 regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair. TSPAN3 is a glycosylated protein and it is differentially glycosylated in different tissues (PMID: 27818272).


