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验证数据展示

  • WB analysis of hTERT-RPE1 using 14430-1-AP (same clone as 14430-1-PBS)

    WB analysis of hTERT-RPE1 using 14430-1-AP (same clone as 14430-1-PBS)

    WB result of TSPAN10 antibody (14430-1-AP; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-TSPAN10 transfected hTERT-RPE1 cells. This data was developed using the same antibody clone with 14430-1-PBS in a different storage buffer formulation.

  • IF Staining of hTERT-RPE1 cells using 14430-1-AP (same clone as 14430-1-PBS)

    IF Staining of hTERT-RPE1 cells using 14430-1-AP (same clone as 14430-1-PBS)

    IF result (nuclear and the base of cilia stain) of anti-TSPAN10 (14430-1-AP, 1:50) with human hTERT-RPE1 (MeOH fixation) cells by Dr. Moshe Kim. This data was developed using the same antibody clone with 14430-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

TSPAN10 Polyclonal antibody, PBS Only

TSPAN10 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 14430-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

14430-1-PBS targets TSPAN10 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag5807

Product name: Recombinant human TSPAN10 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 181-355 aa of BC032802

Sequence: SLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAARSGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tetraspanin 10
别名
计算分子量 36.5 kDa
观测分子量36-40 kDa
GenBank蛋白编号BC032802
基因名称 TSPAN10
Gene ID (NCBI) 83882
RRIDAB_2878057
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H1Z9
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TSPAN10 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN10 belongs to the TSPANC8 subfamily, which also include TSPAN5, TSPAN14, TSPAN15, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).

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