• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

TRPV2 Polyclonal antibody

TRPV2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 15991-1-AP

Print datasheet

Synonyms

Osm 9 like TRP channel 2, OTRPC2, TRPV2, VRL, VRL 1, VRL1

验证数据展示

  • WB analysis using 15991-1-AP

    WB analysis using 15991-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 15991-1-AP (TRPV2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inJurkat cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

15991-1-AP targets TRPV2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA
Cited ApplicationsWB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen TRPV2 fusion protein Ag8864 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transient receptor potential cation channel, subfamily V, member 2
Synonyms Osm 9 like TRP channel 2, OTRPC2, TRPV2, VRL, VRL 1, VRL1
Calculated Molecular Weight 764 aa, 86 kDa
Observed Molecular Weight90 kDa
GenBank Accession NumberBC018926
Gene Symbol TRPV2
Gene ID (NCBI) 51393
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y5S1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Transient receptor potential vanilloid 2 (TRPV2), also name as VRL-1, plays a critical role in neuronal development, cardiac function, immunity, and cancer (PMID: 31566564). It has been found to play an essential role in sustained intracellular Ca2+ concentration increase (PMID: 31857697). It's reported that TRPV2 is activated by high temperatures, with a threshold of around 52℃ (PMID: 10201375). The calculated molecular of TRPV2 is 86 kDa, 15991-1-AP can detect the band around 90 kDa.

实验方案

Product Specific Protocols
WB protocol for TRPV2 antibody 15991-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

EMBO Mol Med

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.

Authors - Yi Huang
View Article