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验证数据展示

  • WB analysis using 84517-5-RR (same clone as 84517-5-PBS)

    WB analysis using 84517-5-RR (same clone as 84517-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84517-5-RR (TRPC6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84517-5-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 84517-5-RR (same clone as 84517-5-PBS)

    IF Staining of A549 using 84517-5-RR (same clone as 84517-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A549 cells using TRPC6 antibody (84517-5-RR, Clone: 251552A8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84517-5-PBS in a different storage buffer formulation.

TRPC6 Recombinant monoclonal antibody, PBS Only

TRPC6 Uni-rAb® Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84517-5-PBS

产品说明书

CloneNo. 251552A8

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

FSGS2, Transient receptor protein 6, TRP 6, TRP6, TRP-6

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

84517-5-PBS targets TRPC6 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transient receptor potential cation channel, subfamily C, member 6
别名 FSGS2, Transient receptor protein 6, TRP 6, TRP6, TRP-6
计算分子量 931 aa, 106 kDa
观测分子量130 kDa
GenBank蛋白编号BC093658
基因名称 TRPC6
Gene ID (NCBI) 7225
RRIDAB_3743577
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9Y210
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transient receptor potential canonical (TRPC) channels mediate the influx of different types of cations through the cell membrane and are involved in many functions of the organism (PMID: 28508319). The TRPC subfamily consists of seven members, TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, TRPC7 (PMID: 32872338). TRPC6 is a Ca(2+)-permeable non-selective cation channel expressed in most human tissues. TRPC6 has been considered as potential therapeutic targets for malignant glioma treatment (PMID: 35489424).

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