TRMT10C Recombinant antibody

TRMT10C Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 84991-4-RR

产品说明书

CloneNo. 242522B5

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

WB, ELISA

RG9MTD1, 242522B5, MRPP1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inLNCaP cells, HeLa cells, HepG2 cells, K-562 cells, PC-12 cells, rat heart tissue
Planning an IHC experiment? We recommend our IHCeasy TRMT10C Ready-To-Use IHC Kit. TRMT10C primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84991-4-RR targets TRMT10C in WB, ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, rat
免疫原 TRMT10C fusion protein Ag30642 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 RNA (guanine-9-) methyltransferase domain containing 1
别名 RG9MTD1, 242522B5, MRPP1
计算分子量 47 kDa
观测分子量45 kDa
GenBank蛋白编号NM_017819
基因名称 TRMT10C
Gene ID (NCBI) 54931
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ7L0Y3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

tRNA methyltransferase 10 homolog C (TRMT10C, also known as MRPP1) is involved in mitochondrial RNA processing and modification (PMID: 21593607). It is essential for the 5'-ends processing of mitochondrial tRNAs and plays a critical role in mitochondrial respiration and translation (PMID: 18984158; 29040705). Mutations in TRMT10C may be a cause of mitochondrial disease and highlight the importance of RNA processing for correct mitochondrial function (PMID: 27132592).

实验方案

Product Specific Protocols
WB protocol for TRMT10C antibody 84991-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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