TRIM46 Polyclonal antibody

TRIM46 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 30298-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse, rat, human

应用

WB, IF/ICC, ELISA

FLJ23229, Gene Y protein, GENEY, TRIFIC, TRIM46, tripartite motif containing 46

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse brain tissue, rat brain tissue
Positive IF/ICC detected inHepG2 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:3000
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

30298-1-AP targets TRIM46 in WB, IF/ICC, ELISA applications and shows reactivity with mouse, rat, human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB
经测试反应性 mouse, rat, human
文献引用反应性mouse
免疫原 TRIM46 fusion protein Ag33175 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tripartite motif-containing 46
别名 FLJ23229, Gene Y protein, GENEY, TRIFIC, TRIM46, tripartite motif containing 46
计算分子量 759 aa, 83 kDa
观测分子量83 kDa
GenBank蛋白编号BC069416
基因名称 TRIM46
Gene ID (NCBI) 80128
RRIDAB_3086290
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ7Z4K8
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Tripartite motif-containing protein 46 (TRIM46), a microtubule-associated protein, is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity, and proper neuronal migration. The TRIM46 protein reported in previous studies includes the long isoform TRIM46L (83 kDa) and the short isoform TRIM46S (60 kDa).

实验方案

Product Specific Protocols
WB protocol for TRIM46 antibody 30298-1-APDownload protocol
IF protocol for TRIM46 antibody 30298-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

J Cell Sci

Efficient axonal transport of endolysosomes relies on the balanced ratio of microtubule tyrosination and detyrosination

Authors - Anja Konietzny
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