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验证数据展示

  • WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84661-4-RR (TRIM26 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

  • IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissue slide using 84661-4-RR (TRIM26 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TRIM26 antibody included
  • IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissue slide using 84661-4-RR (TRIM26 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TRIM26 antibody included
  • Affinity and Kinetic Characterization of 84661-4-RR

    Affinity and Kinetic Characterization of 84661-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84661-4-RR against Human TRIM26 were performed. The affinity constant is 47.3 pM.

TRIM26 Recombinant monoclonal antibody, PBS Only

TRIM26 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84661-4-PBS

产品说明书

CloneNo. 242154B5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

242154B5, EC:2.3.2.27, RNF95, TRIM, Tripartite motif-containing protein 26

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy TRIM26 Ready-To-Use IHC Kit. TRIM26 primary antibody included.

产品信息

84661-4-PBS targets TRIM26 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag25546

Product name: Recombinant human TRIM26 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 151-270 aa of BC024039

Sequence: NHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFW

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tripartite motif-containing 26
别名 242154B5, EC:2.3.2.27, RNF95, TRIM, Tripartite motif-containing protein 26
计算分子量 62 kDa
观测分子量 60-70 kDa
GenBank蛋白编号BC024039
基因名称 TRIM26
Gene ID (NCBI) 7726
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ12899
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation. (PMID: 25763818, PMID: 26611359)

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