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验证数据展示

  • WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84661-4-RR (TRIM26 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

  • IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissue slide using 84661-4-RR (TRIM26 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TRIM26 antibody included
  • IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    IHC staining of human rectal cancer using 84661-4-RR (same clone as 84661-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissue slide using 84661-4-RR (TRIM26 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TRIM26 antibody included
  • Affinity and Kinetic Characterization of 84661-4-RR

    Affinity and Kinetic Characterization of 84661-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84661-4-RR against Human TRIM26 were performed. The affinity constant is 47.3 pM.

TRIM26 Recombinant antibody, PBS Only

TRIM26 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84661-4-PBS

产品说明书

CloneNo. 242154B5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

242154B5, EC:2.3.2.27, RNF95, TRIM, Tripartite motif-containing protein 26

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy TRIM26 Ready-To-Use IHC Kit. TRIM26 primary antibody included.

产品信息

84661-4-PBS targets TRIM26 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 TRIM26 fusion protein Ag25546 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tripartite motif-containing 26
别名 242154B5, EC:2.3.2.27, RNF95, TRIM, Tripartite motif-containing protein 26
计算分子量 62 kDa
观测分子量 60-70 kDa
GenBank蛋白编号BC024039
基因名称 TRIM26
Gene ID (NCBI) 7726
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ12899
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation. (PMID: 25763818, PMID: 26611359)