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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98154-1-RR (same clone as 98154-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98154-1-RR (same clone as 98154-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody (98154-1-RR, Clone: 241279D10) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD16. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98154-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98154-1-RR (same clone as 98154-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98154-1-RR (same clone as 98154-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody (98154-1-RR, Clone: 241279D10)(red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98154-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98154-1-RR

    Affinity and Kinetic Characterization of 98154-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98154-1-RR against Human TREM-1/CD354 were performed. The affinity constant is 0.676 nM.

Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody, PBS Only

TREM-1/CD354 Uni-rAb® Recombinant Antibody for FC
Cat No. 98154-1-PBS

产品说明书

CloneNo. 241279D10

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

TREM1, TREM 1, CD354, 241279D10

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98154-1-PBS targets TREM-1/CD354 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

Fusion Protein

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 triggering receptor expressed on myeloid cells 1
别名 TREM1, TREM 1, CD354, 241279D10
计算分子量26kDa
GenBank蛋白编号NM_018643.5
基因名称 TREM1
Gene ID (NCBI) 54210
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ9NP99-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.

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