验证数据展示
经过测试的应用
| Positive WB detected in | mouse heart tissue, rat heart tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:12000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
26607-1-AP targets TRDN in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag24294 Product name: Recombinant human TRDN protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 75-293 aa of BC139910 Sequence: NFSASSIAKIGSDPLKLVRDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDSDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTVAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKGQSPAIPPPLPTEQASRPTPASPALEGKY 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | triadin |
| 别名 | TDN, TRDN, triadin, TRISK, TRISK51 |
| 计算分子量 | 729 aa, 82 kDa |
| 观测分子量 | 39 kDa |
| GenBank蛋白编号 | BC139910 |
| 基因名称 | TRDN |
| Gene ID (NCBI) | 10345 |
| RRID | AB_3085888 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q13061 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TRDN is a complete transmembrane protein connecting the sarcoplasmic reticulum, which has the function of triggering excitation-contraction coupling of skeletal muscle and heart and regulating heart rate. TRDN is significantly expressed in heart and skeletal muscle. Mutations in triadin can lead to malignant ventricular arrhythmias (PMID:33692971).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TRDN antibody 26607-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
