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验证数据展示

  • WB analysis using 66792-1-Ig (same clone as 66792-1-PBS)

    WB analysis using 66792-1-Ig (same clone as 66792-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66792-1-Ig (TRBP antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66792-1-Ig (TRBP antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66792-1-Ig (TRBP antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TRBP Monoclonal antibody, PBS Only

TRBP Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66792-1-PBS

产品说明书

CloneNo. 1C9A10

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IHC, Indirect ELISA

别名

LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

66792-1-PBS targets TRBP in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human
免疫原

CatNo: Ag8269

Product name: Recombinant human TRBP protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-366 aa of BC005860

Sequence: MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 TAR (HIV-1) RNA binding protein 2
别名 LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2
计算分子量 39 kDa
观测分子量 43-46 kDa
GenBank蛋白编号BC005860
基因名称 TRBP
Gene ID (NCBI) 6895
RRIDAB_2882136
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ15633
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. The endogenous TRBP that was present in HEK293 cells, with apparent molecular masses of 43-46 kDa, are expressed in human cells. (PMID: 16142218)