验证数据展示
Planning an IHC experiment? We recommend our IHCeasy TRAF6 Ready-To-Use IHC Kit. TRAF6 primary antibody included.
发表文章中的应用
WB | See 1 publications below |
产品信息
CL647-66498 targets TRAF6 in WB applications and shows reactivity with Human samples.
经测试应用 | Application Description |
文献引用应用 | WB |
经测试反应性 | Human |
文献引用反应性 | human |
免疫原 | TRAF6 fusion protein Ag24696 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | TNF receptor-associated factor 6 |
别名 | RING finger protein 85, RNF85, TRAF6 |
计算分子量 | 522 aa, 60 kDa |
观测分子量 | 60 kDa |
GenBank蛋白编号 | BC031052 |
基因名称 | TRAF6 |
Gene ID (NCBI) | 7189 |
偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
最大激发/发射波长 | 654 nm / 674 nm |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q9Y4K3 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses.
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 647 TRAF6 antibody CL647-66498 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |