• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 86840-3-RR (same clone as 86840-3-PBS)

    WB analysis using 86840-3-RR (same clone as 86840-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86840-3-RR (TOM70 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86840-3-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 86840-3-RR (same clone as 86840-3-PBS)

    IF Staining of HepG2 using 86840-3-RR (same clone as 86840-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using TOM70 antibody (86840-3-RR, Clone: 251874H2 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 86840-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86840-3-RR

    Affinity and Kinetic Characterization of 86840-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86840-3-RR against Human TOM70 were performed. The affinity constant is 2.67 nM.

TOM70 Recombinant monoclonal antibody, PBS Only

TOM70 Uni-rAb® Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 86840-3-PBS

产品说明书

CloneNo. 251874H2

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

TOMM70A, KIAA0719, TOMM, TOMM70, Translocase of outer mitochondrial membrane protein 70

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

86840-3-PBS targets TOM70 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag6027

Product name: Recombinant human TOM70 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 245-608 aa of BC052994

Sequence: KNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
别名 TOMM70A, KIAA0719, TOMM, TOMM70, Translocase of outer mitochondrial membrane protein 70
计算分子量 67 kDa
观测分子量 70 kDa
GenBank蛋白编号BC052994
基因名称 TOM70
Gene ID (NCBI) 9868
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO94826
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TOMM70A (or TOM70) is a mitochondrial import receptor responsible for the import of cytosol synthesized precursor proteins into the mitochondria. Tom70 is a member of the tetratricopeptide repeat (TPR) co-chaperone family and contains a conserved TPR clamp domain for interaction with Hsc70 and Hsp90. Recently overexpression of TOM70 has been linked to chemoresistance to drugs in breast cancer cell lines. It is also believed that Tom70 is significantly associated with breast cancer relapse and may predict the recurrence of ovarian cancer.

||
New chat

Able™

正在加载，请稍候...