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验证数据展示

  • WB analysis using 32165-1-AP (same clone as 32165-1-PBS)

    WB analysis using 32165-1-AP (same clone as 32165-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32165-1-AP (TNRC18 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32165-1-PBS in a different storage buffer formulation.

  • WB analysis using 32165-1-AP (same clone as 32165-1-PBS)

    WB analysis using 32165-1-AP (same clone as 32165-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32165-1-AP (TNRC18 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32165-1-PBS in a different storage buffer formulation.

TNRC18 Polyclonal antibody, PBS Only

TNRC18 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 32165-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

Trinucleotide repeat-containing gene 18 protein, Trinucleotide Repeat Containing 18, Long CAG trinucleotide repeat-containing gene 79 protein, KIAA1856, CAGL79

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

32165-1-PBS targets TNRC18 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag37483

Product name: Recombinant human TNRC18 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1238-1400 aa of BC131808

Sequence: PCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELER

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 trinucleotide repeat containing 18
别名 Trinucleotide repeat-containing gene 18 protein, Trinucleotide Repeat Containing 18, Long CAG trinucleotide repeat-containing gene 79 protein, KIAA1856, CAGL79
计算分子量31 kDa
观测分子量29 kDa
GenBank蛋白编号BC131808
基因名称 TNRC18
Gene ID (NCBI) 84629
RRIDAB_3670212
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDO15417
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Trinucleotide repeat containing 18 (TNRC18, also known as CAGL79 and KIAA1856) is a nucleic-acid-binding protein, which recognizes H3K9me3 to mediate the silencing of ERV class I (ERV1) elements and acts as a chromatin-associated regulator of ERVs (PMID: 27980689; 37938770). It is located in the cytosol, mitochondrion, and nucleus (PMID: 19262598). The mutation in TNRC18 may cause Fazio-Londe disease (PMID: 38188848).

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