验证数据展示
产品信息
98182-1-PBS targets TNFRSF9/CD137 in FC applications and shows reactivity with mouse samples.
经测试应用 | FC Application Description |
经测试反应性 | mouse |
免疫原 | FusionProtein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | tumor necrosis factor receptor superfamily, member 9 |
别名 | Ly63, Ila, CD137, 4-1BB ligand receptor, 4-1BB |
计算分子量 | 28 kDa |
GenBank蛋白编号 | NM_001077509.1 |
基因名称 | Tnfrsf9 |
Gene ID (NCBI) | 21942 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | P20334 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)