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TMEM45A Polyclonal antibody

TMEM45A Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 27534-1-AP

Print datasheet

Synonyms

DERP7, DNAPTP4, TMEM45A, transmembrane protein 45A

验证数据展示

  • WB analysis using 27534-1-AP

    WB analysis using 27534-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 27534-1-AP (TMEM45A antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA431 cells, MDA-MB-231 cells, SKOV-3 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

27534-1-AP targets TMEM45A in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA
Tested Reactivity Human
Immunogen TMEM45A fusion protein Ag24392 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transmembrane protein 45A
Synonyms DERP7, DNAPTP4, TMEM45A, transmembrane protein 45A
Observed Molecular Weight75 kDa
GenBank Accession NumberBC040355
Gene Symbol TMEM45A
Gene ID (NCBI) 55076
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NWC5
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TMEM45A, also known as DERP7, DNAPTP4, or FLJ10134, is a transmembrane protein belonging to the TMEM family. TMEM45A is highly expressed in keratinocytes and its expression correlates with keratinization, suggesting a role in normal epidermal physiology(PMID: 22954140; PMID: 24689342). TMEM45A promotes cell proliferation, migration, and invasion in glioblastoma cells, favors epithelial-mesenchymal transition (EMT) in colorectal cancer and promotes cell proliferation by favoring the G1/S cell cycle transition in ovarian cancer cells (PMID: 37936608).

实验方案

Product Specific Protocols
WB protocol for TMEM45A antibody 27534-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols