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验证数据展示

  • IHC staining of human pancreas using 23731-1-AP (same clone as 23731-1-PBS)

    IHC staining of human pancreas using 23731-1-AP (same clone as 23731-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas slide using 23731-1-AP (TMEM231 Antibody) at dilution of 1:50. (under 10x lens). This data was developed using the same antibody clone with 23731-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas using 23731-1-AP (same clone as 23731-1-PBS)

    IHC staining of human pancreas using 23731-1-AP (same clone as 23731-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas slide using 23731-1-AP (TMEM231 Antibody) at dilution of 1:50. (under 40x lens). This data was developed using the same antibody clone with 23731-1-PBS in a different storage buffer formulation.

  • IF Staining of MDCK using 23731-1-AP (same clone as 23731-1-PBS)

    IF Staining of MDCK using 23731-1-AP (same clone as 23731-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MDCK cells using TMEM231 antibody (23731-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23731-1-PBS in a different storage buffer formulation.

TMEM231 Polyclonal antibody, PBS Only

TMEM231 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 23731-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, canine

应用

IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

23731-1-PBS targets TMEM231 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, canine samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, canine
免疫原

CatNo: Ag20669

Product name: Recombinant human TMEM231 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 47-316 aa of BC010609

Sequence: GFWLKRSSYEEQPTVRFQHQVLLVALLGPESDGFLAWSTFPAFNRLQGDRLRVPLVSTREEDRNQDGKTDMLHFKLELPLQSTEHVLGVQLILTFSYRLHRMATLVMQSMAFLQSSFPVPGSQLYVNGDLRLQQKQPLSCGGLDARYNISVINGTSPFAYDYDLTHIVAAYQERNVTTVLNDPNPIWLVGRAADAPFVINAIIRYPVEVISYQPGFWEMVKFAWVQYVSILLIFLWVFERIKIFVFQNQVVTTIPVTVTPRGDLCKEHLS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 hypothetical protein FLJ22167
别名
计算分子量 345 aa, 39 kDa
GenBank蛋白编号BC010609
基因名称 TMEM231
Gene ID (NCBI) 79583
RRIDAB_2879312
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H6L2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Transmembrane protein 231 (TMEM231) encodes a 36 kDa two-pass transmembrane protein that is part of the B9 complex and localizes to the base of the ciliary axoneme at the TZ. TMEM231 was first identified as a causative gene for MKS and participates in the formation of the diffusion barrier between the cilia and plasma membrane (PMID: 34912761, 37736303). Tmem231 mutant mice have developmental defects reminiscent of MKS patients, including corticomedullary kidney cysts, polydactyly and hepatic ductal plate malformation (PMID: 25869670).

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