验证数据展示
产品信息
19825-1-PBS targets TMEM176B in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag13918 Product name: Recombinant human TMEM176B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 149-209 aa of BC004358 Sequence: SFIWQTEPFLYIDTVCDRSDPVFPTTGYRWMRRSQENQWQKEECRAYMQMLRKLFTAIRAL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | transmembrane protein 176B |
| 别名 | LR8, Protein LR8, Transmembrane protein 176B |
| 计算分子量 | 270 aa, 29 kDa |
| 观测分子量 | 31 kDa, 23 kDa |
| GenBank蛋白编号 | BC004358 |
| 基因名称 | TMEM176B |
| Gene ID (NCBI) | 28959 |
| RRID | AB_10638313 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q3YBM2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TMEM176B (also known as LR8) is a transmembrane protein belongs to the MS4A family of proteins. It may play a role in the process of maturation of dendritic cells. TMEM176B was first discovered in human lung fibroblasts and is associated with human small cell lung carcinoma. Studies suggest that TMEM176B might be involved in cancer and might serve as targets for antiangiogenic therapy of cancer patients (PMID: 24602018, 22244448). There are two isoforms produced by alternative splicing.
