验证数据展示
经过测试的应用
| Positive WB detected in | K-562 cells, U2OS cells, SiHa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
32692-1-AP targets TMCO7 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag38358 Product name: Recombinant human TMCO7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 331-665 aa of BC015617 Sequence: MAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMVLP 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | transmembrane and coiled-coil domains 7 |
| 别名 | KIAA1746, TANGO6, Transmembrane and coiled-coil domain-containing protein 7, Transport and Golgi organization protein 6 homolog |
| 计算分子量 | 1094 aa, 120 kDa |
| 观测分子量 | 120 kDa |
| GenBank蛋白编号 | BC015617 |
| 基因名称 | TMCO7 |
| Gene ID (NCBI) | 79613 |
| RRID | AB_3742709 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9C0B7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TMCO7, also known as transmembrane and coiled-coil domain 7 or TANGO6. MCO7 is predicted to play a role in protein secretion and is considered an integral component of the membrane. TMCO7 has been implicated in leukemia, with ongoing research focusing on validating its role using in vivo leukemic mouse models and protein localization studies. It is being explored as a potential therapeutic target for acute myeloid leukemia (AML).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TMCO7 antibody 32692-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |

