验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 3 publications below |
产品信息
25042-1-AP targets TMCC2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag19083 Product name: Recombinant human TMCC2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-233 aa of BC131629 Sequence: MKRCRSDELQQQQGEEDGAGLEDAASHLPGADLRPGETTGANSAGGPTSDAGAAAAPNPGPRSKPPDLKKIQQLSEGSMFGHGLKHLFHSRRRSREREHQTSQDSQQHQQQQGMSDHDSPDEKERSPEMHRVSYAMSLHDLPARPTAFNRVLQQIRSRPSIKRGASLHSSSGGGSSGSSSRRTKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQCRPRSSSTTDTALLLADG 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | transmembrane and coiled-coil domain family 2 |
| 别名 | Cerebral protein 11, HUCEP11, hucep-11, KIAA0481, Transmembrane and coiled-coil domains protein 2 |
| 计算分子量 | 709 aa, 77 kDa |
| 观测分子量 | 85-90 kDa |
| GenBank蛋白编号 | BC131629 |
| 基因名称 | TMCC2 |
| Gene ID (NCBI) | 9911 |
| RRID | AB_2879866 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O75069 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TMCC2 also termed as Cerebral protein 11 or HUCEP11 is a 709 amino acid protein, which is a multi-pass membrane protein and belongs to the TEX28 family. The TMCC2 may have an association with Alzheimer's disease.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TMCC2 antibody 25042-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Mol Neurodegener Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells. | ||
Hum Mol Genet Loss of TMCC2 activates endoplasm reticulum stress and causes auditory hair cell death |